Plasmid-mediated ArmA and RmtB 16S rRNA methylases in Escherichia coli isolated from chickens.

نویسندگان

  • Xiang-Dang Du
  • Cong-Ming Wu
  • He-Bing Liu
  • Xin-Sheng Li
  • Ross C Beier
  • Fang Xiao
  • Shang-Shang Qin
  • Si-Yang Huang
  • Jian-Zhong Shen
چکیده

1. Kimura K, Suzuki S, Wachino J et al. First molecular characterization of group B streptococci with reduced penicillin susceptibility. Antimicrob Agents Chemother 2008; 52: 2890–7. 2. Nagano N, Nagano Y, Kimura K et al. Genetic heterogeneity in pbp genes among clinically isolated group B streptococci with reduced penicillin susceptibility. Antimicrob Agents Chemother 2008; 52: 4258–67. 3. Jones N, Bohnsack JF, Takahashi S et al. Multilocus sequence typing system for group B Streptococcus. J Clin Microbiol 2003; 41: 2530–6. 4. Bisharat N, Jones N, Marchaim D et al. Population structure of group B Streptococcus from a low-incidence region for invasive neonatal disease. Microbiology 2005; 151: 1875–81. 5. Maurer P, Koch B, Zerfass I et al. Penicillin-binding protein 2x of Streptococcus pneumoniae: three new mutational pathways for remodeling an essential enzyme into a resistance determinant. J Mol Biol 2008; 376: 1403–16.

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Plasmid-mediated 16S rRNA methylases in aminoglycoside-resistant Enterobacteriaceae isolates in Shanghai, China.

High-level resistance to aminoglycosides produced by 16S rRNA methylases in Enterobacteriaceae isolates was investigated. The prevalences of armA in Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae were 0.6%, 3.0%, and 10%, respectively. rmtB was more prevalent than armA. Pulsed-field gel electrophoresis patterns indicated that armA and rmtB have spread horizontally and clonally.

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High prevalence of plasmid-mediated 16S rRNA methylase gene rmtB among Escherichia coli clinical isolates from a Chinese teaching hospital

BACKGROUND Recently, production of 16S rRNA methylases by Gram-negative bacilli has emerged as a novel mechanism for high-level resistance to aminoglycosides by these organisms in a variety of geographic locations. Therefore, the spread of high-level aminoglycoside resistance determinants has become a great concern. METHODS Between January 2006 and July 2008, 680 distinct Escherichia coli cli...

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عنوان ژورنال:
  • The Journal of antimicrobial chemotherapy

دوره 64 6  شماره 

صفحات  -

تاریخ انتشار 2009